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Rheumatology
Drug survival of tumor necrosis factor α inhibitors in patients with ankylosing spondylitis in Korea
Hyemin Jeong, Yeong Hee Eun, In Young Kim, Hyungjin Kim, Joong Kyong Ahn, Jaejoon Lee, Eun-Mi Koh, Hoon-Suk Cha
Korean J Intern Med. 2018;33(2):407-416. Published online October 12, 2016
Background/Aims: To evaluate drug survival of the tumor necrosis factor α inhibitors (TNFi) and risk factors for the drug discontinuation in patients with ankylosing spondylitis (AS).
Methods: We retrospectively evaluated 487 AS patients at a single tertiary hospital. Among the TNFi users, drug s..
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Cardiology
Risk factors for poor prognosis in nosocomial infective endocarditis
Ji-won Hwang, Seung Woo Park, Eun Jeong Cho, Ga Yeon Lee, Eun Kyoung Kim, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
Korean J Intern Med. 2018;33(1):102-112. Published online June 2, 2017
Background/Aims: The aim of our study was to compare the characteristics of nosocomial infective endocarditis (NIE) with community-acquired infective endocarditis (CIE) and to determine independent risk factors for in-hospital death.
Methods: We retrospectively reviewed the medical records of 560 ..
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Pulmonology
Epidemiological trend of pulmonary thromboembolism at a tertiary hospital in Korea
Tae Yun Park, Jae-Woo Jung, Jae Chol Choi, Jong Wook Shin, Jae Yeol Kim, Byoung Whui Choi, In Won Park
Korean J Intern Med. 2017;32(6):1037-1044. Published online March 13, 2017
Background/Aims: Despite increasing interest in pulmonary thromboembolism (PTE), data on recent trends in PTE incidence are limited. This study evaluated the recent incidence rate of PTE.
Methods: We performed a retrospective chart review of patients with PTE admitted to Chung-Ang University Hospit..
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Prevalence and risk factors for reduced pulmonary function in diabetic patients: The Korea National Health and Nutrition Examination Survey
Hee Yeon Kim, Tae Seo Sohn, Hannah Seok, Chang Dong Yeo, Young Soo Kim, Jae Yen Song, Young Bok Lee, Dong-Hee Lee, Jae-Im Lee, Tae-Kyu Lee, Seong Cheol Jeong, Mihee Hong, Hiun Suk Chae
Korean J Intern Med. 2017;32(4):682-689. Published online February 1, 2017
Background/Aims: An association between reduced pulmonary function and diabetes has been observed. Our aim was to evaluate the prevalence and risk factors associated with reduced pulmonary function in diabetic patients.
Methods: We analyzed data from the Korea National Health and Nutrition Examinati..
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Gastroenterology
Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus
Joon Ho Moon, Soo Heon Kwak, Hak C. Jang
Korean J Intern Med. 2017;32(1):26-41. Published online January 1, 2017
Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold hi..
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Nephrology
Determinants and burden of chronic kidney disease in a high-risk population in Korea: results from a cross-sectional study
Yong Un Kang, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2016;31(5):920-929. Published online January 13, 2016
Background/Aims: This study aimed to investigate the prevalence of chronic kidney disease (CKD) and associated risk factors in a high-risk population in Korea.
Methods: A total of 6,045 participants aged ≥ 65 years (mean age, 73.0 ± 5.5) with diabetes or hypertension were enrolled. Participants w..
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Pulmonology
Bleeding complications in critically ill patients with liver cirrhosis
Jaeyoung Cho, Sun Mi Choi, Su Jong Yu, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Jinwoo Lee
Korean J Intern Med. 2016;31(2):288-295. Published online January 25, 2016
Background/Aims: Patients with liver cirrhosis (LC) are at risk for critical events leading to Intensive Care Unit (ICU) admission. Coagulopathy in cirrhotic patients is complex and can lead to bleeding as well as thrombosis. The aim of this study was to investigate bleeding complications in critica..
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Nephrology
Advanced chronic kidney disease: a strong risk factor for Clostridium difficile infection
Sun Chul Kim, Min Young Seo, Jun Yong Lee, Ki Tae Kim, Eunjung Cho, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho, Hyoung-Kyu Kim
Korean J Intern Med. 2016;31(1):125-133. Published online December 28, 2015
Background/Aims: It has been suggested that chronic kidney disease (CKD) is a risk factor for Clostridium difficile infection (CDI) and is associated with increased mortality among patients infected with C. difficile. However, recent studies of the clinical impact of CKD on CDI in Asia..
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Cardiology
Predictive value of CHADS2 score for cardiovascular events in patients with acute coronary syndrome and documented coronary artery disease
In Sook Kang, Wook Bum Pyun, Gil Ja Shin
Korean J Intern Med. 2016;31(1):73-81. Published online December 28, 2015
Background/Aims: The CHADS2 score, used to predict the risk of ischemic stroke in atrial fibrillation (AF) patients, has been reported recently to predict ischemic stroke in patients with coronary heart disease, regardless of the presence of AF. However, little data are available regardin..
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Gastroenterology
Trends in Helicobacter pylori eradication rates by first-line triple therapy and related factors in eradication therapy
Sung Eun Kim, Moo In Park, Seun Ja Park, Won Moon, Youn Jung Choi, Ji Hyun Cheon, Hye Jung Kwon, Ki Hwan Ku, Chang Hun Yoo, Jae Hyun Kim, Gyu Won Lee, Sung Eun Song
Korean J Intern Med. 2015;30(6):801-807. Published online October 30, 2015
Background/Aims: Trends in successful eradication of Helicobacter pylori using first-line triple therapy, consisting of a proton pump inhibitor, amoxicillin, and clarithromycin, have been understudied. We evaluated H. pylori eradication rates at a single center over the last 10 years a..
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Incidence of and risk factors for thyroid dysfunction during peginterferon α and ribavirin treatment in patients with chronic hepatitis C
Yong Hwang, Won Kim, So Young Kwon, Hyung Min Yu, Jeong Han Kim, Won Hyeok Choe
Korean J Intern Med. 2015;30(6):792-800. Published online October 30, 2015
Background/Aims: Thyroid dysfunction (TD) is more likely to occur in patients with chronic hepatitis C (CHC) and is particularly associated with interferon (IFN) treatment. The purpose of this study was to investigate the incidence, outcomes, and risk factors for TD during pegylated interferon (PEG-..
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Prevalence of and risk factors for endogenous endophthalmitis in patients with pyogenic liver abscesses
In Hyung Park, Chung Hwan Jun, Jin Woo Wi, Seon Young Park, Wan Sik Lee, Sook In Jung, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2015;30(4):453-459. Published online June 29, 2015
Background/Aims: Although pyogenic liver abscesses (PLAs) can be successfully treated, the visual prognosis of patients with endogenous endophthalmitis (EE) associated with a PLA is poor. Early diagnosis and prompt intervention may salvage useful vision. Therefore, we investigated risk factors for E..
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Rheumatology
Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy
Na Ri Kim, Eon Jeong Nam, Jong Wan Kang, Hyun Seok Song, Churl Hyun Im, Young Mo Kang
Korean J Intern Med. 2014;29(6):814-821. Published online October 31, 2014
Background/Aims: We investigated the electromyography (EMG) findings and demographic, clinical, and laboratory features that may predict the development of malignancy in patients with idiopathic inflammatory myopathy (IIM).
Methods: In total, 61 patients, 36 with dermatomyositis and 25 with polymyo..
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Cardiology
The incidence and predictors of overall adverse effects caused by low dose amiodarone in real-world clinical practice
Hack-Lyoung Kim, Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Myung-A Kim, Joo-Hee Zo
Korean J Intern Med. 2014;29(5):588-596. Published online August 28, 2014
Background/Aims: Most current knowledge regarding amiodarone toxicity derives from clinical trials. This study was performed to investigate the incidence and risk factors of overall adverse effects of amiodarone in real-world practice using a large sample size.
Methods: Between January 1, 2000 and ..
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Pulmonology
Prevalence and risk factors for reflux esophagitis in patients with chronic obstructive pulmonary disease
Seo Woo Kim, Jin Hwa Lee, Yun Su Sim, Yon Ju Ryu, Jung Hyun Chang
Korean J Intern Med. 2014;29(4):466-473. Published online June 27, 2014
Background/Aims: Gastroesophageal reflux disease is one of the most common causes of chronic cough and is a potential risk factor for the exacerbation of chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the prevalence and risk factors for reflux esophagitis (RE)..
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Cardiology
Impact of family history on the presentation and clinical outcomes of coronary heart disease: data from the Korea Acute Myocardial Infarction Registry
Choongki Kim, Hyuk-Jae Chang, Iksung Cho, Ji Min Sung, Donghoon Choi, Myung Ho Jeong, Yang Soo Jang,
Korean J Intern Med. 2013;28(5):547-556. Published online August 14, 2013
Background/AimsFamily history (FHx) of coronary heart disease (CHD) is a well-known risk factor for CHD. However, the prognostic implication of FHx has not been established clearly in patients with acute myocardial infarction (AMI). MethodsIn t..
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Epidemiology of Ciprofloxacin Resistance and Its Relationship to Extended-Spectrum β-Lactamase Production in Proteus mirabilis Bacteremia
Kyung Mok Sohn, Cheol-In Kang, Eun-Jeong Joo, Young Eun Ha, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Jae-Hoon Song
Korean J Intern Med. 2011;26(1):89-93. Published online March 3, 2011
Background/AimsWe evaluated the clinical features of ciprofloxacin-resistant Proteus mirabilis bacteremia and risk factors for ciprofloxacin resistance. MethodsFrom October 2000 to July 2009, 37 patients with clinically signific..
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The Risk Factors and Outcome of Acute Kidney Injury in the Intensive Care Units
Woo Young Park, Eun Ah Hwang, Mi Hyun Jang, Sung Bae Park, Hyun Chul Kim
Korean J Intern Med. 2010;25(2):181-187. Published online June 1, 2010
Background/AimsAcute kidney injury (AKI) is a common and serious complication in critically ill patients, especially in the intensive care unit (ICU). The present study was performed to evaluate the occurrence rate of AKI using the RIFLE (increasing severity classes risk, inju..
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Chest Computed Tomography (CT) Immediately after CT-Guided Transthoracic Needle Aspiration Biopsy as a Predictor of Overt Pneumothorax
Tae June Noh, Chang Hoon Lee, Young Ae Kang, Sung-Youn Kwon, Ho-Il Yoon, Tae Jung Kim, Kyung Won Lee, Jae Ho Lee, Choon-Taek Lee
Korean J Intern Med. 2009;24(4):343-349. Published online November 27, 2009
Background/AimsThis study examined the correlation between pneumothorax detected by immediate post-transthoracic needle aspiration-biopsy (TTNB) chest computed tomography (CT) and overt pneumothorax detected by chest PA, and investigated factors that might influence the correl..
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Blood Stream Infections by Candida glabrata and Candida krusei: A Single-Center Experience
Hee Kyoung Choi, Su Jin Jeong, Han Sung Lee, Bum Sik Chin, Suk Hoon Choi, Sang Hoon Han, Myung Soo Kim, Chang Oh Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
Korean J Intern Med. 2009;24(3):263-269. Published online August 26, 2009
Background/AimsThe increasing incidence of Candida glabrata and Candida krusei infections is a significant problem because they are generally more resistant to fluconazole. We compared the risk factors associated with C. glabrata
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